Project TitleRaman Biosensor for Multianalyte Detection
Track Code2002-073
Short Description

 Novel implantable biosensors for detecting multiple clinically relevant analytes in real time

#sensor #biosensor #diagnostics #detection #healthcare


Northwestern University researchers have developed a novel nanoscale biosensor that can be implanted under the skin or in the eye to monitor levels of several clinically important compounds in the blood. This research group has shown that surface- enhanced Raman sensor (SERS) is capable of measuring levels of glucose in vivo, which has historically been a difficult task. Continuous monitoring of blood glucose levels has the potential to reduce the incidence of diabetes related morbidity and mortality and could revolutionize diabetes management by interfacing with implantable insulin pumps. Furthermore, this nanosensor can be modified to detect other compounds in blood, like lactic acid, urea, pesticides and so on. Therefore, many other chronic diseases, like kidney disorders, could be monitored using the same convenient method. Ultimately, devices like this one have the potential to change how clinicians diagnose any number of acute and chronic disorders, as well as help patients manage their symptoms. 

TagsSENSOR: biosensor, DIAGNOSTICS: detection, HEALTHCARE: Diagnostic Tool
Posted DateMar 3, 2015 10:33 AM


Matthew Glucksberg

Richard P Van Duyne*

Karen E Shafer-Peltier

Christy L Haynes

Joseph T Walsh

Chanda Ranjit Yonzon

Nilam C Shan

Olga Lyandres

Douglass Stuart

Jonathan M Yuen


  • Diabetes monitoring and management
  • Implantable diagnostics


  • Sensitive
  • Small size
  • Versatile- various analytes can be detected (urea, lactate, pesticides, pollutants etc.)


IP Status

Issued US patent number 8,592,226

Marketing Contact

Vara Josyula, PhD

Invention Manager 

(p) 847.491.4456