Details

Project TitleNovel Synthetic Route to Diazaperopyrenium Dication
Track Code2013-072, 2013-073
Short Description

A novel perylene derivative with a wide range of applications including graphene exfoliation, catalysis and therapeutics

#chemical #methods #materials #biomedical

Abstract

Perylenes are a class of polycyclic organic molecules, which have mostly garnered attention due to their flourescence. While perylenes had been used in biological imaging and organic photoconductors, their applications were limited because of their insolubility and lack of methods for efficient modification. The Stoddart group at Northwestern University has developed two methods for installing handles onto the starting molecule, which allow for further modifications, as well as an oxidation technique for aromatization of the perylene dications into diazaperopyrenium dications (DDs). The resulting class of molecules have wide ranging biological and industrial applications. Most notably, one of the DDs has demonstrated toxicity against several cancer cell lines, and others are powerful catalysts. In addition, the novel molecules generated by the Stoddart group are soluble in water and inexpensive and simple to generate.

 
TagsCHEMICAL: methods, MATERIALS: biomedical
 
Posted DateJan 20, 2015 11:46 AM

Inventor(s)

J. Fraser Stoddart*

Ashish N. Basuray

Karel J. Hartlieb

Leah Witus

Srinivasan Sampath

Henri-Pierre Jacquot de Rouville

Applications

  • Graphene exfoliation under mild conditions
  • Photocatalysis (water splitting, carbon dioxide reduction)
  • Cancer therapy
  • Solar cells
  • Fluorescent probes (organic and water soluble)
  • Organic dyes
  • Antibody detection

Advantages

  • Water soluble
  • Cost-effective
  • Easy to functionalize

Publications

IP Status

US patent application has been filed.

Marketing Contact

Sarah Kamper, PhD

Invention Associate

(p) 847-491-5095

(e) sarah.kamper@northwestern.edu